Why Renophase?

Pioneers in Photodynamic Peels and Cellular Longevity

RENOPHASE is a French laboratory dedicated to cellular skin longevity, grounded in research on epigenetics and longevity pathways, a modern framework for understanding why skin quality changes over time and how to support long-term resilience.

For over 40 years of R&D, RENOPHASE has developed high-tolerance, precision-driven protocols designed to restore balance, improve visible skin quality, and elevate professional outcomes whether used as standalone treatments or integrated with advanced energy-based devices.

The main goal is to address skin dysfunctions and origin of inflammation, correct signs of aging, protect and maintain the skin in optimal condition for as long as possible, Skin Longevity.

“Cell longevity is the life cycle of your skin.It tells a story, your story, and I’m interested in it.” Dr. Michèle Eymard

Turning an Accident Into a Mission

RENOPHASE was founded by Dr. Michèle Eymard du Vernet, an industrial pharmacist specialized in formulation (galenic science). After a severe car accident at 24 and a long reconstructive journey, she committed her career to one question: how can skin regain balance and visible quality with the highest possible tolerance?

That personal turning point became a scientific mission developing professional protocols and homecare that support skin function at the source, so confidence can follow.

RENOPHASE is designed as a complete system: professional protocols in clinic, supported by Intensive & Precision Home Care. Home routines are built to reinforce results between visits—supporting daily hydration, comfort, and visible refinement, so each appointment lasts longer.

OUR MISSION

to repair and regenerate the skin, the mirror of self-confidence

Since 1984, Renophase technology has been based on a research platform that has generated unique processes in the development of innovative formulations, key to their effectiveness and recognition by the international medical community.

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Renophase commitment

- TO THE ECOLOGICAL TRANSITION -

Minimizing Waste

Preferring short loops

Responsible Formulation

Commited to protecting the oceans

Impact of packaging

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Minimising waste

In each of our manufacturing processes, we minimize waste in order to reduce our impact on the environment as much as possible.

Promote the short circuit

Production, packaging and shipping circuits are grouped on the same site.

Responsible formulation

Our cosmetics are the result of rigorously responsible formulation, with a list of ingredients carefully selected for their effectiveness and minimal impact on the environment, guaranteeing beauty and well-being while respecting nature and your health.

Committed to protecting the oceans

In each of our manufacturing processes, we minimise waste to mitigate our impact on the environment

Production, packaging and shipping circuits are grouped on the same site.

Our primary packaging is recyclable. All our new secondary cardboard packaging is FSC mix certified and is therefore designed from a blend of fibres from sustainably managed FSC approved forests as well as recycled materials.

OUR STORY

– IN CHRONOLOGY –

GENESIS

Car crash that disfigured my face and revealed my life mission. Double degree in pharmaceuticals and pharmacy. Further studies in the drug delivery curriculum

Founding (1983)

Defining my quest, I founded Laboratoires Renophase.

Collaboration (1987)

The result of an international research collaboration in the field of vascular and cellular oxygenation. Development of a molecular complex for the treatment of cellulite.

Renewal (1995)

I present the first peels with glycolic acid to French medical professionals. A whole renewal in aesthetic dermatology.

Invention (1997)

In full flow of fruit acids, I invent a remarkably biocompatible and antioxidant formulation. Glycolic Acid is now accessible to more fragile skin.

Mission accomplished!

Development of a combination of molecules to compensate for deficiencies related to menopause... a bet that paid off! An antioxidant molecular complex capable of reversing the visible effects of time.

Photo-rejuvenation (2007)

2007 Photodynamic peels, a global innovation, for assisting the process of photo-rejuvenation, with LED and IPL. A new method in dermatological treatments applied to many areas, such as acne, marks, wrinkles, looseness and scars.

New technology (2012)

A new patented technology in dermatological treatments for mature skin and scars.

4R PROTOCOL (2016)

Development of a technological cosmeceutical, which is precise and very active. PROTOCOL 4R

Dermatological innovation (2020)

Innovations in Integrative Dermatology for multi-level results and overall improvement of the skin in its texture, structure and volume.

Ecocert (2023)

Ecocert certification for the development, manufacture and marketing of Ecocert Cosmos Organic-certified formulations.

40 years
R&D

Renophase research is based on the science of cell longevity genes and epigenetics. These two of the most advanced areas of research in the scientific world represent a new understanding of the causes of cell ageing and open up treatment prospects in a wide range of fields.

It is important to understand cellular aging including skin aging begins with an inflammatory state that disrupts the epigenetic balance.

Dr Michèle Eymard

Epigenetics & Longevity

Renophase is an advanced skin longevity technology based on Epigenetic.

This innovation is grounded in the science of cellular longevity genes, designed to protect and maintain the cellular health and modify the appearance of the skin over the long term, Well Aging.

The dermatological procedures combine innovative biological precursors with non-invasive or hybrid laser technologies to optimize and enhance cell regeneration.

The main goal is to address skin dysfunctions and origin of inflammation, correct signs of aging, protect and maintain the skin in optimal condition for as long as possible, Skin Longevity.

Immediate & long lasting results

Integrative® Dermatology

Improving skin disorders such acne, melasma and rosacea

Retargeting®

Deep treatment of elasticity and arquitecture of skin

R-bio

Biological balance for tired and stress skins

INTENSIVE AND PRECISION HOME CARE PROGRAMS

Integrative® COSMECEUTICAL

Our cosmeceutical home protocol continues, extending the results of your Regenerative Treatments. Daily reinforcement.

Renophase technology is based on a research platform which for 40 years has generated galenic formulations built on unique manufacturing and molecular complexation processes. These are the key to their effectiveness and their recognition by the international medical profession.

MADE IN FRANCE

Integrative® Energy Medicine & Cellular Longevity

The convergence of action of synchronized biological precursor and energy medicine represents a ground breaking approach in regenerative dermatological treatments. improving skin heath, oxidative stress protection collagen stimulation and tissue regeneration.

This unic technology is declined in advanced integrated skin longevity procedures designed to protect cellular heath, optimize skin functionality in non ablative or hybrid laser or IPL protocols.

This scientifically grounded and precision-driven procedure represents a significant advancement in the field of cellular longevity, offering a targeted and holistic approach to slowing down the cycles that lead to aging and promoting long-term cellular resilience.

Biological precursors for cellular optimization

Biological precursors are molecules involved in biological cycles that maintain cellular health and the optimal balance of skin functions, known as homeostasis.

They optimize the synthesis of structural proteins such as collagen and elastin, and stimulate skin regeneration mechanisms.

Cell Aging & Quality Cell Epigenetic

Cellular aging is a natural process in which cells lose functionality and regenerative capacity, affecting tissue and organ quality.

Skin epigenetics refers to all the changes in gene expression in skin cells , by regulating how and when certain genes are activated or deactivated. These mechanisms are reversible and allow the skin to adapt to its environment.

Dr. Michèle Eymard